cov khoom
Zoo L-Glutathione Txo CAS 70-18-8 rau Kev Kho Hniav Glutathione
Product details
MF: C10H17N3O6S
PIB: 307.32
CAS: 70-18-8 Nr
1.Glutathione yog ib qho tripeptide compound condensed los ntawm glutamic acid, cysteine thiab glycine los ntawm peptide bonds.Nws yog qhov tseem ceeb tshaj plaws uas tsis muaj molecular mercaptan nyob rau hauv mammalian hlwb nyob rau hauv antioxidant kev nyuaj siab.
2.Glutathione (GSH) yog ib qho tripeptide compound tsim los ntawm condensation ntawm glutamic acid, cysteine thiab glycine los ntawm peptide bonds.Nws lub npe tshuaj yog γ- Cov qauv qauv ntawm l-glutamyl-l-cysteyl-glycine yog qhia hauv daim duab 1chemicalbook.Raws li cov qauv qauv hauv daim duab, GSH txawv ntawm lwm cov peptides thiab cov proteins.Muaj ib daim ntawv cog lus tshwj xeeb peptide hauv nws cov molecule, uas yog ua los ntawm glutamic acid γ- Carboxyl (- COOH) thiab cysteine α- Peptide daim ntawv cog lus tsim los ntawm condensation ntawm amino - (- NH2).
3.Qhov hnyav molecular ntawm glutathione yog 307.33, lub melting point yog 189 ~ 193 ℃ (decomposition), siv lead ua tsis muaj xim, pob tshab, slender kem, thiab isoelectric point yog 5.93.Nws yog soluble hauv dej, dilute cawv, kua ammonia thiab methyl formamide, tab sis insoluble hauv cawv, ether thiab acetone.Tsuas yog GSH muaj lub cev ua haujlwm hauv lub cev, thiab GSSG tuaj yeem ua nws txoj haujlwm tseem ceeb ntawm lub cev tom qab txo qis.GSH tsis yooj yim rau khaws cia nyob rau hauv dej siab, thiab nws tuaj yeem khaws cia kom ruaj khov rau lub sijhawm ntev tsuas yog thaum cov dej tswj tau qis dua 0.3.Cov kev tshawb fawb tau pom tias nyob rau hauv cov vitamin ccchemicalbook aqueous tov uas muaj GSH (ph3.3), vim muaj zog txo cov vitamin C, GSH nyob rau hauv cov tshuaj yuav tsis oxidized rau GSSG, tab sis nws decomposition ceev yog ceev;GSSG nyob rau hauv vitamin C aqueous tov yuav tsis hloov mus rau hauv GSH, thiab nws cia stability yog zoo heev.Ntxiv mus, GSSG noj los ntawm lub qhov ncauj tuaj yeem raug txo kom GSH nyob rau sab sauv ntawm cov hnyuv me, thiab qhov chaw ntawm cov hnyuv me epithelial hlwb γ- GTP (uas decomposes GSH rau glutamic acid thiab Cys Gly) thiab dipeptidase kuj tseem tuaj yeem ua si nws lub cev tseem ceeb. kev ua haujlwm.
4.Glutathione dav muaj nyob rau hauv cov tsiaj thiab nroj tsuag, thiab nws cov ntsiab lus nyob rau hauv baker cov poov xab, hom qoob mog thiab tsiaj lub siab yog siab heev, mus txog 100 ~ 1000mg / 100g;Nws kuj yog nplua nuj nyob rau hauv tib neeg thiab tsiaj cov ntshav, xws li 26chemicalbook ~ 34mg / 100g hauv tib neeg cov ntshav, 58 ~ 73mg / 100g hauv cov ntshav qaib, 10 ~ 15mg / 100g hauv cov ntshav npua thiab 14 ~ 22mg / 100g hauv cov ntshav dev.GSH kuj pom muaj nyob rau hauv ntau yam zaub, qos yaj ywm thiab nplej.
Daim ntawv thov
1.Reduced glutathione yog ib qho me me molecule peptide, uas muaj nyob rau hauv ntau cov kab mob, tshwj xeeb tshaj yog nyob rau hauv daim siab hlwb.Nws tuaj yeem tiv thaiv daim siab cell membrane, txhawb lub siab enzyme kev ua haujlwm, thiab ua ke nrog ntau yam tshuaj lom neeg hauv chemicalbook kom detoxify.Nws muaj cov txiaj ntsig zoo ntawm daim siab raug mob, mob siab rau daim siab thiab lwm yam kab mob uas tshwm sim los ntawm kev siv tshuaj lom, haus dej cawv thiab lwm yam laj thawj.
2.Nws muaj lub luag haujlwm ntawm kev tiv thaiv oxidation, tshem tawm cov dawb radicals, detoxification, txhim khu kev tiv thaiv, ncua kev laus, tiv thaiv qog noj ntshav, tiv thaiv hluav taws xob puas tsuaj thiab lwm yam.
3.Biochemical reagents thiab tshuaj tua kab mob feem ntau yog siv rau kev lom ntawm cov hlau hnyav, acrylonitrile, fluoride, carbon monoxide thiab cov kuab tshuaj organic.
4.Endogenous antioxidants uas ua lub luag haujlwm tseem ceeb hauv kev txo qis ntawm cov pa oxygen reactive tsim thaum lub sijhawm cell metabolism thiab ua pa sai.Glutathione-S-transferase catalyzes tsim glutathione sulfide nrog xenobiotics, leukotrienes thiab lwm yam molecules nrog electrophilic chaw.Glutathione kuj tsim cov nyiaj disulfide nrog cysteine residues hauv cov protein.Los ntawm cov txheej txheem no, nws tuaj yeem muaj qhov txawv txav ntawm kev txo qis kev ua haujlwm ntawm cov tshuaj tiv thaiv kab mob.
